| Date | Location | Result | |
| 11/02/21 | Scranton, PA | Marywood 3, Gwynedd Mercy Univ. 1 (25-19,21-25,25-17,25-15) | Box score |
| 10/29/21 | Union, NJ | Kean 3, Gwynedd Mercy Univ. 0 (25-20,25-8,25-11) | Box score |
| 10/27/21 | Hackettstown, NJ | Gwynedd Mercy Univ. 3, Centenary (NJ) 0 (25-14,26-24,25-19) | Box score |
| Oct 26, 2021 | Gwynedd Valley, Pa. | Gwynedd Mercy Univ. 3, Immaculata Univ. 0 (25-12,25-11,25-23) | Box score |
| Oct 21, 2021 | Gywnedd Valley, Pa. | Rutgers-Camden 3, Gwynedd Mercy Univ. 0 (25-21,25-19,25-18) | Box score |
| 10/20/21 | Aston, PA | Neumann 3, Gwynedd Mercy Univ. 0 (25-16,25-20,25-16) | Box score |
| Oct 16, 2021 | Gwynedd Valley, Pa. | Haverford College 3, Gwynedd Mercy Univ. 0 (25-15,25-13,25-18) | Box score |
| Oct 16, 2021 | Gwynedd Valley, Pa. | Marymount University 3, Gwynedd Mercy Univ. 0 (25-13,25-14,25-16) | Box score |
| 10/13/21 | Scranton, PA | Marywood 3, Gwynedd Mercy Univ. 1 (28-24,25-20,20-25,25-18) | Box score |
| Oct 09, 2021 | Gwynedd Valley, Pa. | Gwynedd Mercy Univ. 3, Ramapo College 0 (25-17,25-20,25-22) | Box score |
| Oct 09, 2021 | Gwynedd Valley, Pa. | Moravian University 3, Gwynedd Mercy Univ. 0 (25-15,25-22,25-21) | Box score |
| 10/08/21 | Towson, MD | Goucher 3, Gwynedd Mercy Univ. 2 (25-23,25-23,19-25,28-30,15-11) | Box score |
| Oct 05, 2021 | Gwynedd Valley, Pa. | Cabrini College 3, Gwynedd Mercy Univ. 0 (25-18,25-20,25-12) | Box score |
| Oct 02, 2021 | Gwynedd Valley, Pa. | FDU-Florham 3, Gwynedd Mercy Univ. 0 (25-21,25-22,25-15) | Box score |
| 10/2/2021 | Gwynedd Valley, Pa. | Gwynedd Mercy Univ. 3, Penn State-Abington 1 (25-16,28-30,25-17,25-17) | Box score |
| 09/29/21 | Gwynedd Valley, PA | Penn St.-Berks 3, Gwynedd Mercy Univ. 0 (25-17,26-24,25-21) | Box score |
| 09/28/21 | Langhorne, PA | Gwynedd Mercy Univ. 3, Cairn 1 (23-25,25-23,25-15,25-18) | Box score |
| Sep 25, 2021 | Gwynedd Valley, PA | Notre Dame (MD) 3, Gwynedd Mercy 2 (25-17,25-22,18-25,16-25,15-10) | Box score |
| Sep 25, 2021 | Gwynedd Valley, PA | Arcadia 3, Gwynedd Mercy 0 (25-13,25-14,25-18) | Box score |
| 09/23/21 | Gwynedd Valley, PA | Gwynedd Mercy Univ. 3, Bryn Mawr 0 (25-14,25-15,25-20) | Box score |
| 09/21/21 | Gwynedd Valley, PA | Gwynedd Mercy Univ. 3, Bryn Athyn 0 (25-11,25-15,25-19) | Box score |
| 09/18/21 | Reading, PA | Alvernia 3, Gwynedd Mercy Univ. 2 (17-25,28-26,22-25,25-18,15-13) | Box score |
| 09/18/21 | Reading, PA | Cedar Crest 3, Gwynedd Mercy Univ. 1 (25-19,21-25,25-20,25-14) | Box score |
| 09/16/21 | Clarks Summit, PA | Gwynedd Mercy Univ. 3, Clarks Summit 0 (25-10,25-16,25-19) | Box score |
| 09/15/21 | Lancaster, PA | Lancaster Bible 3, Gwynedd Mercy Univ. 0 (25-13,25-10,25-20) | Box score |
| 09/09/21 | Gwynedd Valley, PA | Ursinus 3, Gwynedd Mercy Univ. 1 (21-25,25-17,26-24,25-15) | Box score |
| 09/08/21 | Chester, PA | Widener 3, Gwynedd Mercy Univ. 1 (17-25,25-12,25-16,25-19) | Box score |
| 09/04/21 | Reading, PA | Gwynedd Mercy Univ. 3, Penn College 0 (25-14,25-21,25-18) | Box score |
| 09/04/21 | Reading, PA | Albright 3, Gwynedd Mercy Univ. 2 (20-25,20-25,25-21,25-17,15-9) | Box score |